Rs4680 – הבדלי גרסאות

מספר מחקרים בגנטיקה של האישיות בדקו את הקשר של הפולימורפיזם [[פסיכולוגיית התכונות|לתכונות אישיות]], כולל [[מופנמות ומוחצנות|מוחצנות]], סלידת סיכון וחיפוש אחר חידושים<ref>{{Cite journal|title=Association of the functional catechol-O-methyltransferase VAL158MET polymorphism with the personality trait of extraversion|last=Martin Reuter & Juergen Hennig|date=July 2005|journal=[[NeuroReport]]|issue=10|doi=10.1097/00001756-200507130-00020|volume=16|pages=1135–1138|pmid=15973162}}</ref> <ref>{{Cite journal|title=An association study of catechol-O-methyltransferase and monoamine oxidase A polymorphisms and personality traits in Koreans|last=[[Se Joo Kim]], [[Young Shin Kim]], [[Shin Young Kim]], [[Hong Shick Lee]] & [[Chan-Hyung Kim]]|date=June 2006|journal=[[Neuroscience Letters]]|issue=1–2|doi=10.1016/j.neulet.2006.03.006|volume=401|pages=154–158|pmid=16584839}}</ref> <ref>{{Cite journal|title=A possible association between the Val158Met polymorphism of the catechol-O-methyl transferase gene and the personality trait of harm avoidance in Japanese healthy subjects|last=[[Ryota Hashimoto]], [[Hiroko Noguchi]], [[Hiroaki Hori]], [[Kazutaka Ohi]], [[Yuka Yasuda]], [[Masatoshi Takeda]] & [[Hiroshi Kunugi]]|date=November 2007|journal=[[Neuroscience Letters]]|issue=1|doi=10.1016/j.neulet.2007.09.036|volume=428|pages=17–20|pmid=17945417}}</ref> <ref>{{Cite journal|title=COMT polymorphisms and anxiety-related personality traits|last=[[Murray B. Stein]], [[Margaret Daniele Fallin]], [[Nicholas J. Schork]] & [[Joel Gelernter]]|date=November 2005|journal=[[Neuropsychopharmacology (journal)|Neuropsychopharmacology]]|issue=11|doi=10.1038/sj.npp.1300787|volume=30|pages=2092–2092|pmid=15956988}}</ref> <ref>{{Cite journal|title=Personality in relation to genetic liability for schizophrenia and bipolar disorder: Differential associations with the COMT Val108/158Met polymorphism|last=[[Amy L. Silberschmidt]] & [[Scott Sponheim]]|date=March 2008|journal=[[Schizophrenia Research]]|issue=1|doi=10.1016/j.schres.2007.12.467|volume=100|pages=316–324|pmc=2682527|pmid=18201871}}</ref>.